Coupling of ortho-substituted aryl chlorides with bulky amides

被引：27

作者：

Falk, Florian C. ^{[1
]}

Froehlich, Roland ^{[2
]}

Paradies, Jan ^{[1
]}

机构：

[1] Karlsruhe Inst Technol, Inst Organ Chem, D-76131 Karlsruhe, Germany

[2] Univ Munster, Inst Organ Chem, D-48149 Munster, Germany

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 39期

关键词：

PALLADIUM-CATALYZED AMINATION; DOUBLE N-ARYLATION; REDUCTIVE ELIMINATION; PHOSPHINE OXIDES; LIGANDS; HALIDES; AMINES; SCOPE; HETEROARYL; ARYLAMINES;

D O I：

10.1039/c1cc14844c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Voluminous amides were coupled with deactivated, sterically hindered aryl chlorides in excellent yields providing products, which have not been efficiently accessible by transition metal catalysis so far. Application of an unsymmetric bisphosphine ligand was critical for the high catalytic activity.

引用

页码：11095 / 11097

页数：3

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