Highly active iridium(I) complexes for catalytic hydrogen isotope exchange

被引:130
作者
Brown, Jack A. [1 ]
Irvine, Stephanie [1 ]
Kennedy, Alan R. [1 ]
Kerr, William J. [1 ]
Andersson, Shalini [2 ]
Nilsson, Goeran N. [2 ]
机构
[1] Univ Strathclyde, Dept Pure & Appl Chem, WestCHEM, Glasgow G1 1XL, Lanark, Scotland
[2] AstraZeneca, R&D Molndal, Med Chem, SE-43183 Molndal, Sweden
关键词
D O I
10.1039/b715938b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Practically convenient methods have been developed for the preparation of new iridium complexes, possessing bulky N-heterocyclic carbene and phosphine ligands; these routinely handled complexes are highly active catalysts within directed hydrogen isotope exchange processes.
引用
收藏
页码:1115 / 1117
页数:3
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