New Catalytic Approaches towards the Enantioselective Halogenation of Alkenes

被引：232

作者：

Hennecke, Ulrich ^{[1
]}

机构：

[1] Univ Munster, Inst Organ Chem, D-48151 Munster, Germany

来源：

CHEMISTRY-AN ASIAN JOURNAL | 2012年 / 7卷 / 03期

关键词：

asymmetric catalysis; cyclization; electrophilic addition; halogens; organocatalysis; HIGHLY EFFICIENT SYNTHESIS; ASYMMETRIC BROMOLACTONIZATION; SEMIPINACOL REARRANGEMENT; ALLYLIC ALCOHOLS; IONS; HALOCYCLIZATION; FLUORINATION; BROMONIUM; OLEFINS; ACID;

D O I：

10.1002/asia.201100856

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The addition of electrophilic reagents to the carboncarbon double bond is one of the most fundamental reactions in organic chemistry. Halogen electrophiles constitute probably the most important class of electrophiles and have been widely used to induce electrophilic addition reactions to alkenes like halolactonizations or dihalogenations. Despite their long history and high importance, catalytic, asymmetric variants of these reactions have been underdeveloped until very recently. During the last two years this has changed and many novel approaches have been reported. This review aims to cover these new developments through discussing the common themes as well as the suggested mechanistic scenarios.

引用

页码：456 / 465

页数：10

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