Introduction to micro-analytical systems: bioanalytical and pharmaceutical applications

被引：129

作者：

Huikko, K

Kostiainen, R

Kotiaho, T

机构：

[1] Univ Helsinki, Dept Pharm, Vikki Drug Discovery Technol Ctr, FIN-00014 Helsinki, Finland

[2] Univ Helsinki, Dept Pharm, Div Pharmaceut Chem, FIN-00014 Helsinki, Finland

来源：

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES | 2003年 / 20卷 / 02期

关键词：

fabrication technology; analytical instruments; miniaturization;

D O I：

10.1016/S0928-0987(03)00147-7

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

This review presents a brief overview of recent developments in miniaturization of analytical instruments utilizing microfabrication technology. The concept 'Micro-Total Analysis Systems (mu-TAS)', also termed 'Lab-on-a-chip', and the latest progresses in the development of microfabricated separation devices and on-chip detection techniques are discussed. Applications of micro-analytical methods to bioanalytical and pharmaceutical studies are also described, including chemical reactions, assays, and analytical separations of biomolecules in micro-scale. (C) 2003 Elsevier B.V. All rights reserved.

引用

页码：149 / 171

页数：23

共 164 条

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