Diminished vancomycin and daptomycin susceptibility during prolonged bacteremia with methicillin-resistant Staphylococcus aureus

被引:21
作者
Bennett, Jason W. [1 ]
Murray, Clinton K. [1 ]
Holmes, Robert L. [2 ]
Patterson, Jan E. [3 ,4 ]
Jorgensen, James H. [5 ]
机构
[1] Brooke Army Med Ctr, Infect Dis MCHE MDI, Dept Med, Ft Sam Houston, TX 78234 USA
[2] Wilford Hall USAF Med Ctr, Dept Infect Dis, San Antonio, TX 78201 USA
[3] Univ Texas Hlth Sci Ctr San Antonio, Dept Med Infect Dis & Pathol, San Antonio, TX 78229 USA
[4] S Texas Vet Hlth Care Syst, San Antonio, TX 78229 USA
[5] Univ Texas Hlth Sci Ctr San Antonio, Dept Pathol, San Antonio, TX 78229 USA
关键词
vancomycin tolerance; daptomycin resistance; MRSA bacteremia; minimum inhibitory concentration; bactericidal effect;
D O I
10.1016/j.diagmicrobio.2007.11.002
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
An elderly patient with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia was treated sequentially with vancomycin plus rifampin then daptomycin plus gentamicin. The MRSA strain developed diminished susceptibility to vancomycin (MIC increase and tolerance), daptomycin, and gentamicin, and resistance to rifampin during therapy. (C) 2008 Elsevier Inc. All rights reserved.
引用
收藏
页码:437 / 440
页数:4
相关论文
共 22 条
[1]  
[Anonymous], 2006, METH DIL ANT SUSC TE
[2]   INCIDENCE AND CHARACTERISTICS OF ANTIBIOTIC-TOLERANT STRAINS OF STAPHYLOCOCCUS-AUREUS [J].
BRADLEY, JJ ;
MAYHALL, CG ;
DALTON, HP .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1978, 13 (06) :1052-1057
[3]  
Clinical and Laboratory Standards Institute, 2006, M100S16 CLIN LAB STA
[4]  
CLSI, 1999, METHODS DETERMINING
[5]   Correlation between reduced daptomycin susceptibility and vancomycin resistance in vancomycin-intermediate Staphylococcus aureus [J].
Cui, LZ ;
Tominaga, E ;
Neoh, HM ;
Hiramatsu, K .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2006, 50 (03) :1079-1082
[6]   SERIOUS STAPHYLOCOCCAL INFECTIONS WITH STRAINS TOLERANT TO BACTERICIDAL ANTIBIOTICS [J].
DENNY, AE ;
PETERSON, LR ;
GERDING, DN ;
HALL, WH .
ARCHIVES OF INTERNAL MEDICINE, 1979, 139 (09) :1026-1031
[7]   Antibiotic resistance - A vancomycin surprise [J].
Gilmore, MS ;
Hoch, JA .
NATURE, 1999, 399 (6736) :524-+
[8]   Development of Daptomycin resistance in vivo in methicillin-resistant Staphylococcus aureus [J].
Hayden, MK ;
Rezai, K ;
Hayes, RA ;
Lolans, K ;
Quinn, JP ;
Weinstein, RA .
JOURNAL OF CLINICAL MICROBIOLOGY, 2005, 43 (10) :5285-5287
[9]   Emergence of a clinical daptomycin-resistant Staphylococcus aureus isolate during treatment of methicillin-resistant Staphylococcus aureus bacteremia and osteomyelitis [J].
Marty, FM ;
Yeh, WW ;
Wennersten, CB ;
Venkataraman, L ;
Albano, E ;
Alyea, EP ;
Gold, HS ;
Baden, LR ;
Pillai, SK .
JOURNAL OF CLINICAL MICROBIOLOGY, 2006, 44 (02) :595-597
[10]   Glycopeptide tolerance in Staphylococcus aureus [J].
May, J ;
Shannon, K ;
King, A ;
French, G .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1998, 42 (02) :189-197