Synthesis and evaluation of a 5-membered isoiminosugar as glycosidase inhibitor

被引：18

作者：

Godskesen, M ^{[1
]}

Lundt, I ^{[1
]}

机构：

[1] Tech Univ Denmark, Dept Organ Chem, DK-2800 Lyngby, Denmark

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 32期

关键词：

D O I：

10.1016/S0040-4039(98)01157-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(3R, 4R)-4-hydroxy-3-hydroxymethylpyrrolidine (6) was prepared from D-xylose and found to be a weak inhibitor of alpha-D-, beta-D-glucosidase and alpha-L-fucosidase. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：5841 / 5844

页数：4

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