In-Stem-Labeled Molecular Beacons for Distinct Fluorescent Color Readout

被引:54
作者
Holzhauser, Carolin [1 ]
Wagenknecht, Hans-Achim [1 ]
机构
[1] Karlsruhe Inst Technol, Inst Organ Chem, D-76131 Karlsruhe, Germany
关键词
DNA; energy transfer; molecular beacons; thiazole orange; wavelength shift; DNA HYBRIDIZATION; DESIGN; PROBES; STRATEGY;
D O I
10.1002/anie.201101968
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
DNA traffic lights for hybridization: An efficient energy transfer between thiazole orange and thiazole red in the DNA stem architecture yields a red fluorescence that changes to green emission upon binding to the target oligonucleotide sequence. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:7268 / 7272
页数:5
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