Metals in neurobiology: Probing their chemistry and biology with molecular imaging

被引：1883

作者：

Que, Emily L. ^{[1
]}

Domaille, Dylan W. ^{[1
]}

Chang, Christopher J. ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA

来源：

CHEMICAL REVIEWS | 2008年 / 108卷 / 05期

关键词：

D O I：

10.1021/cr078203u

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An overview on the transition metals in neurobiology which focuses on d-block metals zinc, iron, and copper to neurophysiology, aging, and neuropathology is presented. A review is also given on the progress in the development of molecular probes for visualizing zinc, iron, and copper ion pools. Small-molecule synthetic reagents that have been used or may be used to probe zinc, iron and copper in biological settings have also been discussed.

引用

页码：1517 / 1549

页数：33

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