Resolution of methylarylmethanols via oxidation with Nocardia corallina

被引：17

作者：

Pérez, HI ^{[1
]}

Luna, H ^{[1
]}

Manjarrez, N ^{[1
]}

Solis, A ^{[1
]}

机构：

[1] Univ Autonoma Metropolitana, Unidad Xochimilco, Dept Sistemas Biol, Mexico City, DF, Mexico

来源：

TETRAHEDRON-ASYMMETRY | 2001年 / 12卷 / 12期

关键词：

D O I：

10.1016/S0957-4166(01)00307-X

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Ten different racemates of methylarylmethanols were subjected to whole cells of Nocardia corallina B-276 to give, via enantioselective oxidations, the corresponding ketone and the enantiomerically enriched secondary alcohol in moderate yields and excellent e.e.s. The configuration of the resulting alcohol is (R). This procedure permits a very good separation of the racemates of meta- and para-monosubstituted methylarylmethanols. (C) 2001 Published by Elsevier Science Ltd.

引用

页码：1709 / 1712

页数：4

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