Dose rate table for a 32P intravascular brachytherapy source from Monte Carlo calculations

被引:17
作者
Bohm, TD [1 ]
Mourtada, FA
Das, RK
机构
[1] Univ Wisconsin, Dept Med Phys, Madison, WI 53706 USA
[2] Guidant Vasc Intervent, Houston, TX 77054 USA
[3] Univ Wisconsin, Dept Human Oncol, Madison, WI 53792 USA
关键词
Monte Carlo; MCNP; radiochromic film; dosimetry; beta particle; intravascular brachytherapy;
D O I
10.1118/1.1384459
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 [临床医学]; 100207 [影像医学与核医学]; 1009 [特种医学];
摘要
Studies of intravascular brachytherapy to prevent restenosis following angioplasty have shown many promising results. Accurate dose rate tables based on detailed models of the brachytherapy sources are necessary for treatment planning. This work will present an away and along dose rate table for a 27 mm long catheter based P-32 beta source. MD-55-2 radiochromic film has been exposed at five different depths (0.5 mm-4 mm) in a polystyrene phantom using a 27 mm long Guidant 32P beta source. The total dose to the active region of the film was determined using the absolute detector response of the MD-55-2 radiochromic film. The Monte Carlo code MCNP4B2 was also used to calculate the dose to the active region of the film using a detailed model of the source, encapsulation, and radiochromic film. The dose to film calculations showed good agreement with the measurements presented in this work with an average difference of 7%. The Monte Carlo calculations were also verified against previously published depth dose in water measurements determined using radiochromic film and plastic scintillator. The depth dose calculations in water showed good agreement with the previously published measurements with the calculations being about 2.5% lower than the film measurements and about 2.5% higher than the scintillator measurements. This work then uses the verified Monte Carlo code to present a dose rate table for the 32P intravascular beta source. (C) 2001 American Association of Physicists in Medicine.
引用
收藏
页码:1770 / 1775
页数:6
相关论文
共 14 条
[1]
Measurements and Monte Carlo calculations to determine the absolute detector response of radiochromic film for brachytherapy dosimetry [J].
Bohm, TD ;
Pearson, DW ;
Das, RK .
MEDICAL PHYSICS, 2001, 28 (02) :142-146
[2]
BRIESMEISTER JF, 1997, LA13709M MCNP
[3]
BRIESMEISTER JF, 1997, LA12625M MCNP
[4]
Determination of a calibration factor for the nondestructive assay of Guidant 32P brachytherapy sources [J].
Collé, R ;
Zimmerman, BE ;
Soares, CG ;
Coursey, BM .
APPLIED RADIATION AND ISOTOPES, 1999, 50 (05) :835-841
[5]
Accuracy of Monte Carlo photon transport simulation in characterizing brachytherapy dosimeter energy-response artefacts [J].
Das, RK ;
Li, Z ;
Perera, H ;
Williamson, JF .
PHYSICS IN MEDICINE AND BIOLOGY, 1996, 41 (06) :995-1006
[6]
GROVE NB, 1971, NUCL DATA TABLES, V10, P205
[7]
HALBLEIB JA, 1992, SAND911634
[8]
Jenkins T M., 1988, Monte Carlo Transport of Electrons and Photons
[9]
Dosimetry characterization of 32P catheter-based vascular brachytherapy source wire [J].
Mourtada, FA ;
Soares, CG ;
Seltzer, SM ;
Lott, SH .
MEDICAL PHYSICS, 2000, 27 (08) :1770-1776
[10]
Intravascular brachytherapy physics: Report of the AAPM Radiation Therapy Committee Task Group No. 60 [J].
Nath, R ;
Amols, H ;
Coffey, C ;
Duggan, D ;
Jani, S ;
Li, ZF ;
Schell, M ;
Soares, C ;
Whiting, J ;
Cole, PE ;
Crocker, I ;
Schwartz, R .
MEDICAL PHYSICS, 1999, 26 (02) :119-152