Photoacoustic Doppler flow measurement in optically scattering media

被引：55

作者：

Fang, Hui ^{[1
]}

Maslov, Konstantin ^{[1
]}

Wang, Lihong V. ^{[1
]}

机构：

[1] Washington Univ, Opt Imaging Lab, Dept Biomed Engn, St Louis, MO 63130 USA

来源：

APPLIED PHYSICS LETTERS | 2007年 / 91卷 / 26期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1063/1.2825569

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

We recently observed the photoacoustic Doppler effect from flowing small light-absorbing particles. Here, we apply the effect to measure blood-mimicking fluid flow in an optically scattering medium. The light scattering in the medium decreases the amplitude of the photoacoustic Doppler signal but does not affect either the magnitude or the directional discrimination of the photoacoustic Doppler shift. This technology may hold promise for a new Doppler method for measuring blood flow in microcirculation with high sensitivity. (c) 2007 American Institute of Physics.

引用

页数：3

共 17 条

[1] MODEL FOR LASER DOPPLER MEASUREMENTS OF BLOOD-FLOW IN TISSUE [J].

BONNER, R ;

NOSSAL, R .

APPLIED OPTICS, 1981, 20 (12) :2097-2107

[2]

BRODY WR, 1974, IEEE T BIO-MED ENG, VBM21, P183, DOI 10.1109/TBME.1974.324381

[3] Optical Doppler tomographic imaging of fluid flow velocity in highly scattering media [J].

Chen, ZP ;

Milner, TE ;

Dave, D ;

Nelson, JS .

OPTICS LETTERS, 1997, 22 (01) :64-66

[4] A high-frequency continuous-wave Doppler ultrasound system for the detection of blood flow in the microcirculation [J].

Christopher, DA ;

Burns, PN ;

Armstrong, J ;

Foster, FS .

ULTRASOUND IN MEDICINE AND BIOLOGY, 1996, 22 (09) :1191-1203

[5] The photoacoustic effect generated by an incompressible sphere [J].

Diebold, GJ ;

Beveridge, AC ;

Hamilton, TJ .

JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA, 2002, 112 (05) :1780-1786

[6] THE PHOTOACOUSTIC EFFECT GENERATED BY A SPHERICAL DROPLET IN A FLUID [J].

DIEBOLD, GJ ;

WESTERVELT, PJ .

JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA, 1988, 84 (06) :2245-2251

[7] Microcirculation: Its significance in clinical and molecular medicine [J].

Fagrell, B ;

Intaglietta, M .

JOURNAL OF INTERNAL MEDICINE, 1997, 241 (05) :349-362

[8] Photoacoustic doppler effect from flowing small light-absorbing particles [J].

Fang, Hui ;

Maslov, Konstantin ;

Wang, Lihong V. .

PHYSICAL REVIEW LETTERS, 2007, 99 (18)

[9] High-frequency color flow imaging of the microcirculation [J].

Goertz, DE ;

Christopher, DA ;

Yu, JL ;

Kerbel, RS ;

Burns, PN ;

Foster, FS .

ULTRASOUND IN MEDICINE AND BIOLOGY, 2000, 26 (01) :63-71

[10]

MASLOV K, IN PRESS J BIOMED OP

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