Synthetic applications of epoxide hydrolases

被引：199

作者：

Archelas, A ^{[1
]}

Furstoss, R ^{[1
]}

机构：

[1] Univ Mediterranee, UMR CNRS 6111, Fac Sci Luminy, Grp Biocatalyse & Chim Fine, F-13288 Marseille 09, France

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 2001年 / 5卷 / 02期

关键词：

D O I：

10.1016/S1367-5931(00)00179-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

There have been several recent advances in the area of biocatalysed hydrolytic kinetic resolution of epoxides using 'newly discovered' enzymes (i.e. epoxide hydrolases). These biocatalysts, two of which will become commercially available in the near future, appear to be highly promising tools for fine organic synthesis, as they enable the preparation of various epoxides and/or their corresponding diols in enantiopure form.

引用

页码：112 / 119

页数：8

共 59 条

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