Merrifield, alpha-methoxyphenyl (MAMP) resin; A new versatile solid support for the synthesis of secondary amides.

被引：11

作者：

Brown, DS ^{[1
]}

Revill, JM ^{[1
]}

Shute, RE ^{[1
]}

机构：

[1] Zeneca Pharmaceut, Lead Discovery Dept, Macclesfield SK10 4TG, Cheshire, England

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 46期

关键词：

D O I：

10.1016/S0040-4039(98)01892-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis and initial reactivity of a new resin, termed MAMP (Merrifield, Alpha-Methoxy Phenyl), which is useful for the on-resin synthesis and mild acidolytic cleavage of compounds containing secondary amide functionality, is reported. Synthesis of a model peptoid utilising MAMP-resin is described. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：8533 / 8536

页数：4

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