Copper-mediated trifluoromethylation of arylboronic acids by trifluoromethyl sulfonium salts

被引：125

作者：

Zhang, Cheng-Pan ^{[1
]}

Cai, Ji ^{[1
]}

Zhou, Chang-Bing ^{[1
]}

Wang, Xiao-Ping ^{[1
,2
]}

Zheng, Xing ^{[2
]}

Gu, Yu-Cheng ^{[3
]}

Xiao, Ji-Chang ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China

[2] Univ S China, Inst Pharm & Pharmacol, Hengyang, Hunan, Peoples R China

[3] Syngenta, Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 33期

关键词：

S-(TRIFLUOROMETHYL)DIBENZOTHIOPHENIUM; FLUOROALKYLATION; REAGENTS; AGENTS;

D O I：

10.1039/c1cc13460d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The ligand-free trifluoromethylation of arylboronic acids with a [Ph2SCF3](+)[OTf](-)/Cu(0) system has been carefully investigated. Aryl-, alkenyl- and heteroarylboronic acids with a variety of functional groups were suitable substrates for this reaction. It is suggested that a CuCF3 species is formed under the reaction conditions.

引用

页码：9516 / 9518

页数：3

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