Facile, solvent and ligand free iron catalyzed direct functionalization of N-protected tetrahydroisoquinolines and isochroman

被引：164

作者：

Ghobrial, Michael ^{[1
]}

Harhammer, Karin ^{[1
]}

Mihovilovic, Marko D. ^{[1
]}

Schnuerch, Michael ^{[1
]}

机构：

[1] Vienna Univ Technol, Inst Appl Synthet Chem, A-1060 Vienna, Austria

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 46期

基金：

奥地利科学基金会;

关键词：

SP(3) C-H; BOND FORMATION; TERTIARY-AMINES; COUPLING REACTIONS; ANODIC CYANATION; ACTIVATION; ADJACENT; ALKYNYLATION; ALCOHOLS; NITROGEN;

D O I：

10.1039/c0cc02491k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient method for an iron catalyzed oxidative indolation and methoxyphenylation of N-protected tetrahydroisoquinolines and isochroman is described including subsequent facile deprotection.

引用

页码：8836 / 8838

页数：3

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