Successful Treatment of an Adolescent With Naegleria fowleri Primary Amebic Meningoencephalitis

被引：89

作者：

Linam, W. Matthew ^{[1
]}

Ahmed, Mubbasheer ^{[2
]}

Cope, Jennifer R. ^{[3
]}

Chu, Craig ^{[2
]}

Visvesvara, Govinda S. ^{[3
]}

da Silva, Alexandre J. ^{[3
]}

Qvarnstrom, Yvonne ^{[3
]}

Green, Jerril ^{[2
]}

机构：

[1] Arkansas Childrens Hosp, Pediat Infect Dis Sect, Little Rock, AR 72202 USA

[2] Arkansas Childrens Hosp, Pediat Crit Care Sect, Little Rock, AR 72202 USA

[3] Ctr Dis Control & Prevent, Atlanta, GA USA

来源：

PEDIATRICS | 2015年 / 135卷 / 03期

关键词：

SEVERE BACTERIAL-MENINGITIS; FREE-LIVING AMEBAS; IN-VITRO; BALAMUTHIA-MANDRILLARIS; AMPHOTERICIN-B; ACANTHAMOEBA SPP; BRAIN-INJURY; MOUSE MODEL; HYPOTHERMIA; INFECTION;

D O I：

10.1542/peds.2014-2292

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Naegleria fowleri is a thermophilic, free-living ameba that causes primary amebic meningoencephalitis. The infections are nearly always fatal. We present the third well-documented survivor of this infection in North America. The patient's survival most likely resulted from a variety of factors: early identification and treatment, use of a combination of antimicrobial agents (including miltefosine), and management of elevated intracranial pressure based on the principles of traumatic brain injury.

引用

页码：E744 / E748

页数：5

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