The α-alkylation of methyl ketones with primary alcohols promoted by nickel nanoparticles under mild and ligandless conditions

被引：45

作者：

Alonso, Francisco ^{[1
]}

Riente, Paola ^{[1
]}

Yus, Miguel ^{[1
]}

机构：

[1] Univ Alicante, Fac Ciencias, Inst Quim Organ, Dept Quim Organ, E-03080 Alicante, Spain

来源：

SYNLETT | 2007年 / 12期

关键词：

alpha-alkylation; ketones; primary alcohols; nickel; nanoparticles;

D O I：

10.1055/s-2007-984522

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Nickel nanoparticles have been found to promote the a-alkylation of ketones with primary alcohols in the absence of any added ligand or base, under mild reaction conditions.

引用

页码：1877 / 1880

页数：4

共 22 条

[1] Preparation of nickel(0) nanoparticles by arene-catalysed reduction of different nickel chloride-containing systems [J].

Alonso, F. ;

Calvino, J. J. ;

Osante, I. ;

Yus, M. .

JOURNAL OF EXPERIMENTAL NANOSCIENCE, 2006, 1 (04) :419-433

[2] Highly stereoselective semihydrogenation of alkynes promoted by nickel(0) nanoparticles [J].

Alonso, F ;

Osante, M ;

Yus, M .

ADVANCED SYNTHESIS & CATALYSIS, 2006, 348 (03) :305-308

[3] A new straightforward and mild preparation of nickel(0) nanoparticles [J].

Alonso, F ;

Calvino, JJ ;

Osante, I ;

Yus, M .

CHEMISTRY LETTERS, 2005, 34 (09) :1262-1263

[4] The NiCl2-Li-arene(cat.) combination: A versatile reducing mixture [J].

Alonso, F ;

Yus, M .

CHEMICAL SOCIETY REVIEWS, 2004, 33 (05) :284-293

[5] Highly selective hydrogenation of multiple carbon-carbon bonds promoted by nickel(0) nanoparticles [J].

Alonso, Francisco ;

Osante, Inaki ;

Yus, Miguel .

TETRAHEDRON, 2007, 63 (01) :93-102

[6] Conjugate reduction of α,β-unsaturated carbonyl compounds promoted by nickel nanoparticles [J].

Alonso, Francisco ;

Osante, Inaki ;

Yus, Miguel .

SYNLETT, 2006, (18) :3017-3020

[7] LIQUID-PHASE REGIOSELECTIVE 1,4-HYDROGENATION OF BENZYLIDENE KETONES ON RH/ALPO4 CATALYSTS [J].

CABELLO, JA ;

CAMPELO, JM ;

GARCIA, A ;

LUNA, D ;

MARINAS, JM .

JOURNAL OF ORGANIC CHEMISTRY, 1986, 51 (10) :1786-1790

[8]

CAINE D, 2000, MODERN CARBONYL CHEM

[9]

Caine D., 1991, Comprehensive Organic Synthesis, V3, P1

[10] A ruthenium-catalyzed one-pot method for α-alkylation of ketones with aldehydes [J].

Cho, Chan Sik ;

Shim, Sang Chul .

JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2006, 691 (20) :4329-4332

← 1 2 3 →