Three-Dimensional Paper Microfluidic Devices Assembled Using the Principles of Origami

被引:429
作者
Liu, Hong
Crooks, Richard M. [1 ]
机构
[1] Univ Texas Austin, Dept Chem & Biochem, Ctr Electrochem, Austin, TX 78712 USA
关键词
D O I
10.1021/ja2071779
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We report a method, based on the principles of origami (paper folding), for fabricating three-dimensional (3-D) paper microfluidic devices. The entire 3-D device is fabricated on a single sheet of flat paper in a single photolithographic step. It is assembled by simply folding the paper by hand. Following analysis, the device can be unfolded to reveal each layer. The applicability of the device to chemical analysis is demonstrated by colorimetric and fluorescence assays using multilayer microfluidic networks.
引用
收藏
页码:17564 / 17566
页数:3
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