PEG-polymer-supported liquid-phase combinatorial synthesis of structurally diverse 2,3-dihydro-4-pyridones

被引：10

作者：

Guo, HC ^{[1
]}

Wang, Z ^{[1
]}

Ding, KL ^{[1
]}

机构：

[1] Shanghai Med Univ, Shanghai Inst Organ Chem, State Key Lab Organomet Chem, Shanghai 200032, Peoples R China

来源：

SYNTHESIS-STUTTGART | 2005年 / 07期

关键词：

PEG; liquid-phase synthesis; combinatorial; aza Diels-Alder reactions; 2,3-dihydro-4-pyridones;

D O I：

10.1055/s-2005-861857

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient liquid-phase synthetic protocol for the construction of structurally diverse 2,3-dihydro-4-pyridones on soluble polymer support by the aza Diels-Alder reaction has been developed, which utilized a one-pot three-component reaction of either PEG-supported amine, aromatic aldehydes and the Danishefsky's diene, or PEG-supported aldehyde, aromatic amines and Danishefsky's diene.

引用

页码：1061 / 1068

页数：8

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