Optical detection of glucose and acetylcholine esterase inhibitors by H2O2-sensitive CdSe/ZnS quantum dots

被引：212

作者：

Gill, Ron ^{[1
]}

Bahshi, Lily ^{[1
]}

Freeman, Ronit ^{[1
]}

Willner, Itamar ^{[1
]}

机构：

[1] Hebrew Univ Jerusalem, Ctr Nanosci, Inst Chem, IL-91904 Jerusalem, Israel

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 09期

关键词：

biosensors; enzymes; nanobiotechnology; nanoparticles; quantum dots;

D O I：

10.1002/anie.200704794

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) The coupling of oxidases with fluorophore-labeled CdSe/ZnS quantum dots enables the ratiometric fluorescence analysis of enzyme activities and their substrates by the interaction between the biocatalytically generated H2O2 and the quantum dots. The method has been applied to the analyis of glucose and the inhibition of acetylcholine esterase. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：1676 / 1679

页数：4

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