Transmembrane anion transport by synthetic systems

被引：75

作者：

Haynes, Cally J. E. ^{[1
]}

Gale, Philip A. ^{[1
]}

机构：

[1] Univ Southampton, Sch Chem, Southampton SO17 1BJ, Hants, England

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 29期

基金：

英国工程与自然科学研究理事会;

关键词：

ION-CHANNEL FORMATION; CHLORIDE TRANSPORT; CYSTIC-FIBROSIS; CONFORMATIONAL CONTROL; MEMBRANE TRANSPORTERS; PRODIGIOSINS; BICARBONATE; ANTICANCER; CALIXARENES; ALTERS;

D O I：

10.1039/c1cc12061a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This highlight examines recent advances in the development of synthetic membrane transporters for anions, highlighting the underlying principles of transporter design and the promising applications of such transporters to biological systems including potential future treatments for diseases like cystic fibrosis which is caused by dysregulation of chloride transport across epithelial cell membranes.

引用

页码：8203 / 8209

页数：7

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