Zn/C-Catalyzed Cycloaddition of Azides and Aryl Alkynes

被引:110
作者
Meng, Xu [1 ]
Xu, Xiaoyun [1 ]
Gao, Tingting [1 ]
Chen, Baohua [1 ]
机构
[1] Lanzhou Univ, State Key Lab Appl Organ Chem, Key Lab Nonferrous Met Chem & Resources Utilizat, Lanzhou 730000, Peoples R China
基金
美国国家科学基金会;
关键词
Zinc; Cycloaddition; Heterogeneous catalysis; Azides; Click chemistry; ONE-POT SYNTHESIS; CLICK-CHEMISTRY; 1,4-DISUBSTITUTED 1,2,3-TRIAZOLES; TERMINAL ALKYNES; 1,3-DIPOLAR CYCLOADDITION; ORGANIC AZIDES; IN-SITU; REGIOSELECTIVE SYNTHESIS; HUISGEN CYCLOADDITION; EFFICIENT SYNTHESIS;
D O I
10.1002/ejoc.201000610
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Charcoal impregnated with zinc was able to catalyze the cycloaddition of organic azides and alkynes to provide the corresponding 1,4-disubstituted 1,2,3-triazoles and 1,4,5-trisubstituted 1,2,3-triazoles in good to excellent yields. Note-worthy was that the novel and heterogeneous catalyst was successfully applied in this cycloaddition reaction for the first time and could also be easily recycled.
引用
收藏
页码:5409 / 5414
页数:6
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