Copper nanoparticles in click chemistry: an alternative catalytic system for the cycloaddition of terminal alkynes and azides

被引：123

作者：

Alonso, Francisco ^{[1
,2
]}

Moglie, Yanina ^{[1
,2
,3
]}

Radivoy, Gabriel ^{[3
]}

Yus, Miguel ^{[1
,2
]}

机构：

[1] Univ Alicante, Fac Ciencias, Dept Quim Organ, E-03080 Alicante, Spain

[2] Univ Alicante, ISO, E-03080 Alicante, Spain

[3] Univ Nacl Sur, Inst Quim Sur INQUISUR, Dept Quim, RA-8000 Bahia Blanca, Buenos Aires, Argentina

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 20期

关键词：

Click chemistry; Cycloaddition; Alkynes; Azides; Copper nanoparticles; 1,4-DISUBSTITUTED 1,2,3-TRIAZOLES; 1,3-DIPOLAR CYCLOADDITIONS; REGIOSELECTIVE SYNTHESIS; MEDICINAL CHEMISTRY; REDUCTION; LIGATION; TRIAZOLE; HALIDES;

D O I：

10.1016/j.tetlet.2009.02.220

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Readily prepared copper nanoparticles have been found to effectively catalyse the 1,3-dipolar cycloaddition of a variety of azides and alkynes furnishing the corresponding 1,2,3-triazoles in excellent yields. Both the preparation of the nanoparticles and the click reaction proceed in short reaction times. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：2358 / 2362

页数：5

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