Identification of a highly effective asymmetric phase-transfer catalyst derived from α-methylnaphthylamine

被引：82

作者：

Lygo, B ^{[1
]}

Allbutt, B

James, SR

机构：

[1] Univ Nottingham, Sch Chem, Nottingham NG7 2RD, England

[2] AstraZeneca, Proc R&D, Macclesfield SK10 2NA, Cheshire, England

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 30期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1016/S0040-4039(03)01352-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A library of quaternary ammonium salts has been generated via reaction of simple chiral amines with a series of conformationally dynamic biphenyl units. Screening of this library against the alkylation of a glycine imine has led to the identification of a highly effective asymmetric phase-transfer catalyst derived from alpha-methylnaphthylamine. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：5629 / 5632

页数：4

共 25 条

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