Being More Realistic about the Public Health Impact of Genomic Medicine

被引:34
作者
Hall, Wayne D. [1 ,2 ]
Mathews, Rebecca [1 ]
Morley, Katherine I. [3 ,4 ]
机构
[1] Univ Queensland, Univ Queensland Ctr Clin Res, Herston, Qld, Australia
[2] Univ Queensland, Queensland Brain Inst, St Lucia, Qld, Australia
[3] Wellcome Trust Sanger Inst, Cambridge, England
[4] Univ Melbourne, Sch Populat Hlth, Ctr Mol Environm Genet & Analyt Epidemiol, Melbourne, Vic 3010, Australia
来源
PLOS MEDICINE | 2010年 / 7卷 / 10期
关键词
GENETIC RISK INFORMATION; WIDE ASSOCIATION; POLICY IMPLICATIONS; NICOTINE ADDICTION; COMPLEX DISEASES; COMMON DISEASES; BREAST-CANCER; PREDICTION; SUSCEPTIBILITY; PREVENTION;
D O I
10.1371/journal.pmed.1000347
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页数:4
相关论文
共 52 条
[41]   Impact of genetic testing on causal models of heart disease and arthritis: An analogue study [J].
Senior, V ;
Marteau, TM ;
Weinman, J .
PSYCHOLOGY & HEALTH, 1999, 14 (06) :1077-1088
[42]   Genetic Epidemiology 7 - Genetic epidemiology and public health: hope, hype, and future prospects [J].
Smith, GD ;
Ebrahim, S ;
Lewis, S ;
Hansell, AL ;
Palmer, LJ ;
Burton, PR .
LANCET, 2005, 366 (9495) :1484-1498
[43]   Value of genetic profiling for the prediction of coronary heart disease [J].
van der Net, Jeroen B. ;
Janssens, A. Cecile J. W. ;
Sijbrands, Eric J. G. ;
Steyerberg, Ewout W. .
AMERICAN HEART JOURNAL, 2009, 158 (01) :105-110
[44]  
van Ommen GJB, 1999, LANCET, V354, pSI5
[45]   Sizing up human height variation [J].
Visscher, Peter M. .
NATURE GENETICS, 2008, 40 (05) :489-490
[46]   Heritability in the genomics era - concepts and misconceptions [J].
Visscher, Peter M. ;
Hill, William G. ;
Wray, Naomi R. .
NATURE REVIEWS GENETICS, 2008, 9 (04) :255-266
[47]   Capital ventures into biology: biosocial dynamics in the industry and science of gambling [J].
Vrecko, Scott .
ECONOMY AND SOCIETY, 2008, 37 (01) :50-67
[48]   Psychosocial impact of breast/ovarian (BRCA 1/2) cancer-predictive genetic testing in a UK multi-centre clinical cohort [J].
Watson, M ;
Foster, C ;
Eeles, R ;
Eccles, D ;
Ashley, S ;
Davidson, R ;
Mackay, J ;
Morrison, PJ ;
Hopwood, P ;
Evans, DGR .
BRITISH JOURNAL OF CANCER, 2004, 91 (10) :1787-1794
[49]   How has the prevalence of cigarette smoking changed among Australian adults? Trends in smoking prevalence between 1980 and 2001 [J].
White, V ;
Hill, D ;
Siahpush, M ;
Bobevski, I .
TOBACCO CONTROL, 2003, 12 :67-74
[50]   Prediction of individual genetic risk to disease from genome-wide association studies [J].
Wray, Naomi R. ;
Goddard, Michael E. ;
Visscher, Peter M. .
GENOME RESEARCH, 2007, 17 (10) :1520-1528