Monotetrahydrofuran annonaceous acetogenins from the seeds of Annona squamosa

被引:23
作者
Chen, Yong [1 ]
Chen, Jiang-wei [1 ]
Li, Xiang [1 ]
机构
[1] Nanjing Univ Chinese Med, Coll Pharm, Nanjing 210046, Jiangsu, Peoples R China
关键词
Annona squamosa; Annonaceae; Monotetrahydrofuran annonaceous; acetogenins; Isolation; Structure elucidation; UVARIA-CALAMISTRATA; MONTANA; AGENTS;
D O I
10.1016/j.phytol.2011.08.015
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Three new monotetrahydrofuran annonaceous acetogenins, Annosquamins A-C (1-3) were isolated from the 95% EtOH extract of Annona squamosa seeds, in addition to the known compounds, solamin, annotemoyin-1, uvariamicin-II, uvariamicin-III. Their structures were elucidated by spectroscopic analysis and the relative configurations of bearing tetrahydrofuran rings were established by comparing NMR data with model compounds. (C) 2011 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:33 / 36
页数:4
相关论文
共 20 条
[11]  
Pimenta LPS, 2001, TETRAHEDRON LETT, V42, P8433
[12]  
TAM VT, 1995, B SOC CHIM FR, V132, P324
[13]   Acetogenins of annonaceae -: Part 65 -: Glaucabellin and glaucaflorin, two acetogenins from Annona glauca [J].
Waechter, AI ;
Szlosek, M ;
Hocquemiller, R ;
Laurens, A ;
Cavé, A .
PHYTOCHEMISTRY, 1998, 48 (01) :141-145
[14]   16,19-CIS-MURISOLIN AND MURISOLIN-A, 2 NOVEL BIOACTIVE MONO-TETRAHYDROFURAN ANNONACEOUS ACETOGENINS FROM ASIMINA-TRILOBA SEEDS [J].
WOO, MH ;
ZENG, L ;
YE, Q ;
GU, ZM ;
ZHAO, GX ;
MCLAUGHLIN, JL .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1995, 5 (11) :1135-1140
[15]   Two new cytotoxic acetogenins from Annona squamosa [J].
Yang, Hai-Jun ;
Li, Xiang ;
Zhang, Ning ;
Chen, Jian-Wei ;
Wang, Ming-Yan .
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2009, 11 (03) :250-256
[16]   Structure-activity relationships of diverse annonaceous acetogenins against human tumor cells [J].
Yang, Haijun ;
Zhang, Ning ;
Li, Xiang ;
Chen, Jianwei ;
Cai, Baochang .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 19 (08) :2199-2202
[17]   Supercritical fluid CO2 extraction and simultaneous determination of eight annonaceous acetogenins in Annona genus plant seeds by HPLC-DAD method [J].
Yang, Haijun ;
Li, Xiang ;
Tang, Yuping ;
Zhang, Ning ;
Chen, Jianwei ;
Cai, Baochang .
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2009, 49 (01) :140-144
[18]   Recent advances in annonaceous acetogenins [J].
Zeng, L ;
Ye, Q ;
Oberlies, NH ;
Shi, G ;
Gu, ZM ;
He, K ;
McLaughlin, JL .
NATURAL PRODUCT REPORTS, 1996, 13 (04) :275-306
[19]   Calamistrins A and B, two new cytotoxic monotetrahydrofuran annonaceous acetogenins from Uvaria calamistrata [J].
Zhou, GX ;
Zhou, LE ;
Chen, RY ;
Yu, DQ .
JOURNAL OF NATURAL PRODUCTS, 1999, 62 (02) :261-264
[20]   New annonaceous acetogenins from the roots of Uvaria calamistrata [J].
Zhou, GX ;
Chen, RY ;
Zhang, YJ ;
Yu, DQ .
JOURNAL OF NATURAL PRODUCTS, 2000, 63 (09) :1201-1204