Induction treatment before surgery for non-small cell lung cancer

被引:56
作者
Eberhardt, WE
Albain, KS
Pass, H
Putnam, JB
Gregor, A
Assamura, H
Mornex, F
Senan, S
Belderbos, J
Westeel, V
Thomas, M
Van Schil, P
Vansteenkiste, J
Manegold, C
Mirimanoff, RO
Stuschke, M
Pignon, J
Rocmans, P
Shepherds, FA
机构
[1] Duisburg Essen Univ, Sch Med, W German Canc Ctr, Dept Internal Med, D-45122 Essen, Germany
[2] Loyola Univ, Ctr Med, Cardinal Bernardin Canc Ctr, Maywood, IL USA
[3] Wayne State Univ, Detroit, MI USA
[4] Harper Univ Hosp, Karmanos Canc Inst, Detroit, MI USA
[5] MD Anderson Canc Ctr, Houston, TX USA
[6] Edinburgh Canc Ctr, Edinburgh, Midlothian, Scotland
[7] Natl Canc Ctr Hosp, Tsukiji, Japan
[8] Ctr Hosp Lyon, Radiat Oncol Dept, Lyon, France
[9] VU Univ Med Ctr, Amsterdam, Netherlands
[10] Antoni Van Leeuwenhoek Hosp, Netherlands Canc Inst, Dept Radiotherapy, Amsterdam, Netherlands
[11] J Minjoz Univ Hosp, Chest Dis Dept, Besancon, France
[12] Univ Munster, Dept Hematol Oncol & Resp Med, Munster, Germany
[13] Dept Thorac & Vasc Surg, Antwerp, Belgium
[14] Univ Hosp, Resp Oncol Unit Pulm, Louvain, Belgium
[15] Thoraxklin Heidelberg, Heidelberg, Germany
[16] Univ Lausanne, Dept Radiat Oncol, Lausanne, Switzerland
[17] Duisburg Essen Univ, Sch Med, Dept Radiat Oncol, Essen, Germany
[18] Inst Gustave Roussy, Villejuif, France
[19] Hosp Erasme Univ Libre Bruxelles, Brussels, Belgium
[20] Princess Margaret Hosp, Toronto, ON, Canada
关键词
induction therapy; chemotherapy; radiotherapy; chemoradiation; surgery;
D O I
10.1016/S0169-5002(03)00300-3
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Surgery alone is currently still accepted "standard of care" for patients with operable NSCLC, this includes stages IA and IIB, as well as selected early subsets of IIIA disease. In more advanced and inoperable stage III disease, combinations of chemotherapy and radiotherapy remain the standard treatment approach for patients with good performance status. The role of surgery following induction therapy in these advanced stage III patients is at the moment not conclusively defined. More evidence from randomized trials is clearly needed to tailor treatment for the large
引用
收藏
页码:S9 / S14
页数:6
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