Trifluoromethylation of aryl and heteroaryl halides

被引:286
作者
Roy, Sudipta [1 ]
Gregg, Brian T. [1 ]
Gribble, Gordon W. [2 ]
Le, Van-Duc [1 ]
Roy, Sujata [1 ]
机构
[1] AMRI, Dept Med Chem, 26 Corp Circle, Albany, NY 12212 USA
[2] Dartmouth Coll, Dept Chem, Hanover, NH 03755 USA
关键词
CROSS-COUPLING REACTIONS; PHENYLETHANOLAMINE N-METHYLTRANSFERASE; FORMING REDUCTIVE ELIMINATION; ORGANIC FLUORINE-COMPOUNDS; NUCLEOPHILIC TRIFLUOROMETHYLATION; MEDICINAL CHEMISTRY; 1-AND 2-(TRIFLUOROMETHYL)NAPHTHALENES; BIOLOGICAL EVALUATION; SELECTIVE INHIBITORS; SYNTHETIC METHODS;
D O I
10.1016/j.tet.2011.01.002
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页码:2161 / 2195
页数:35
相关论文
共 212 条
  • [1] Synthesis of aryltrifluoromethylpyridazines application to the synthesis of rod-like molecules as liquid crystals diazines part 46
    Achelle, Sylvain
    Ple, Nelly
    Turck, Alain
    Bouillon, Jean-Philippe
    Portella, Charles
    [J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 2006, 43 (05) : 1243 - 1249
  • [2] Aicher T. D., 2006, PCT Int. Appl., Patent No. [2006057869, WO 2006/057869]
  • [3] AISSAOUI H, 2008, Patent No. 2008078291
  • [4] ALBERATIGIANI D, 2008, Patent No. 7462617
  • [5] CRF ligands via Suzuki and Negishi couplings of 3-pyridyl boronic acids or halides with 2-benzyloxy-4-chloro-3-nitropyridine
    Arvanitis, AG
    Arnold, CR
    Fitzgerald, LW
    Frietze, WE
    Olson, RE
    Gilligan, PJ
    Robertson, DW
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2003, 13 (02) : 289 - 291
  • [6] ASHIMORI A, 1990, CHEM PHARM BULL, V38, P2446
  • [7] Asselin M., 2006, PCT Int, Appl., Patent No. [WO 2006/135839, 2006135839]
  • [8] Design and synthesis of novel 2,3-dihydro-1H-isoindoles with high affinity and selectivity for the dopamine D3 receptor
    Austin, NE
    Avenell, KY
    Boyfield, I
    Branch, CL
    Hadley, MS
    Jeffrey, P
    Johnson, CN
    Macdonald, GJ
    Nash, DJ
    Riley, GJ
    Smith, AB
    Stemp, G
    Thewlis, KM
    Vong, AKK
    Wood, MD
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2001, 11 (05) : 685 - 688
  • [9] The synthesis of salts and esters of perfluorinated dithio- and thiocarboxylic acids from carbon disulfide and carbonyl sulfide reacting with RFSiMe3/F-
    Babadzhanova, LA
    Kirij, NV
    Yagupolskii, YL
    [J]. JOURNAL OF FLUORINE CHEMISTRY, 2004, 125 (07) : 1095 - 1098
  • [10] Heterosubstituted or functionalized derivatives of 1-and 2-(trifluoromethyl)naphthalenes emanating from aryne adducts
    Bailly, F
    Cottet, F
    Schlosser, M
    [J]. SYNTHESIS-STUTTGART, 2005, (05): : 791 - 797