The cell biology of taste

被引：569

作者：

Chaudhari, Nirupa ^{[1
]}

Roper, Stephen D.

机构：

[1] Univ Miami, Miller Sch Med, Dept Physiol & Biophys, Miami, FL 33136 USA

来源：

JOURNAL OF CELL BIOLOGY | 2010年 / 190卷 / 03期

基金：

美国国家卫生研究院;

关键词：

CHORDA TYMPANI NERVE; RECEPTOR-CELLS; BITTER-TASTE; UMAMI TASTE; ACID TASTE; III CELLS; INDIVIDUAL-DIFFERENCES; ORBITOFRONTAL CORTEX; OROSENSORY DETECTION; TRANSIENT RECEPTOR;

D O I：

10.1083/jcb.201003144

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Taste buds are aggregates of 50-100 polarized neuroepithelial cells that detect nutrients and other compounds. Combined analyses of gene expression and cellular function reveal an elegant cellular organization within the taste bud. This review discusses the functional classes of taste cells, their cell biology, and current thinking on how taste information is transmitted to the brain. © 2010 Chaudhari and Roper.

引用

页码：285 / 296

页数：12

共 138 条

[1] Internal body state influences topographical plasticity of sensory representations in the rat gustatory cortex [J].

Accolla, Riccardo ;

Carleton, Alan .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (10) :4010-4015

[2] A novel family of mammalian taste receptors [J].

Adler, E ;

Hoon, MA ;

Mueller, KL ;

Chandrashekar, J ;

Ryba, NJP ;

Zuker, CS .

CELL, 2000, 100 (06) :693-702

[3] Nucleoside triphosphate diphosphohydrolase-2 is the ecto-ATPase of type I cells in taste buds [J].

Bartel, Dianna L. ;

Sullivan, Susan L. ;

Lavoie, Elise G. ;

Sevigny, Jean ;

Finger, Thomas E. .

JOURNAL OF COMPARATIVE NEUROLOGY, 2006, 497 (01) :1-12

[4] Gustatory expression pattern of the human TAS2R bitter receptor gene family reveals a heterogenous population of bitter responsive taste receptor cells [J].

Behrens, Maik ;

Foerster, Susann ;

Staehler, Frauke ;

Raguse, Jan-Dirk ;

Meyerhof, Wolfgang .

JOURNAL OF NEUROSCIENCE, 2007, 27 (46) :12630-12640

[5] Mouse taste cells with glialike membrane properties [J].

Bigiani, A .

JOURNAL OF NEUROPHYSIOLOGY, 2001, 85 (04) :1552-1560

[6]

Breslin PAS, 2006, ADV OTO-RHINO-LARYNG, V63, P152, DOI 10.1159/000093760

[7] Response Latency to Lingual Taste Stimulation Distinguishes Neuron Types Within the Geniculate Ganglion [J].

Breza, Joseph M. ;

Nikonov, Alexandre A. ;

Contreras, Robert J. .

JOURNAL OF NEUROPHYSIOLOGY, 2010, 103 (04) :1771-1784

[8] Individual mouse taste cells respond to multiple chemical stimuli [J].

Caicedo, A ;

Kim, KN ;

Roper, SD .

JOURNAL OF PHYSIOLOGY-LONDON, 2002, 544 (02) :501-509

[9] Taste receptor cells that discriminate between bitter stimuli [J].

Caicedo, A ;

Roper, SD .

SCIENCE, 2001, 291 (5508) :1557-1560

[10] The capsaicin receptor: a heat-activated ion channel in the pain pathway [J].

Caterina, MJ ;

Schumacher, MA ;

Tominaga, M ;

Rosen, TA ;

Levine, JD ;

Julius, D .

NATURE, 1997, 389 (6653) :816-824

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