Virus-PEDOT Nanowires for Biosensing

被引:110
作者
Arter, Jessica A. [1 ]
Taggart, David K. [1 ]
McIntire, Theresa M. [1 ]
Penner, Reginald M. [1 ]
Weiss, Gregory A. [1 ]
机构
[1] Univ Calif Irvine, Dept Chem, Irvine, CA 92697 USA
基金
美国国家科学基金会; 美国国家卫生研究院;
关键词
Nanowires; phage display; PEDOT; biosensing; conducting polymers; CONDUCTING-POLYMER NANOWIRE; LABEL-FREE DETECTION; PHAGE-DISPLAY; POLYPYRROLE NANOTUBES; ELECTRICAL DETECTION; FILAMENTOUS PHAGE; CARBON NANOTUBES; CHEMICAL SENSORS; COAT PROTEIN; FUNCTIONALIZATION;
D O I
10.1021/nl1025826
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The separate fields of conducting polymer based electrochemical sensors and virus based molecular recognition offer; numerous advantages for biosensing Grafting M13 bacteriophage into an array of poly (3 4 ethylenedioxythlophene) (PEDOT) nanowires generated hybrids of conducting polymers and viruses The virus incorporation into the polymeric backbone of PEDOT occurs during electropolymerization via lithographically patterned nanowire electrodeposition The resultant arrays of virus PEDOT nanowires enable real time reagent free electrochemical biosensing of analytes in physiologically relevant buffers
引用
收藏
页码:4858 / 4862
页数:5
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