Diastereoselective synthesis of N,O-psiconucleosides via 1,3-dipolar cycloadditions

被引：42

作者：

Chiacchio, U ^{[1
]}

Corsaro, A

Iannazzo, D

Piperno, A

Rescifina, A

Romeo, R

Romeo, G

机构：

[1] Catania Univ, Dipartimento Sci Chim, Catania, Italy

[2] Univ Messina, Dipartimento Farmacochim, Messina, Italy

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 09期

关键词：

D O I：

10.1016/S0040-4039(00)02325-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A flexible synthetic procedure to access a new and biologically interesting class of N,O-psiconucleosides by 1,3-dipolar cycloaddition of C-ethoxycarbonyl-N-methyl nitrone with ethyl 2-(acetyloxy)acrylate, followed by Vorbruggen nucleosidation and sodium borohydride reduction, is described. (C) 2001 Elsevier Science Ltd. All rights reserved.

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页码：1777 / 1780

页数：4

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