Muscular dystrophies: genes to pathogenesis

被引：160

作者：

Dalkilic, I ^{[1
]}

Kunkel, LM

机构：

[1] Harvard Univ, Sch Med, Dept Genet, Boston, MA 02115 USA

[2] Childrens Hosp, Howard Hughes Med Inst, Div Genet, Boston, MA 02115 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2003年 / 13卷 / 03期

关键词：

D O I：

10.1016/S0959-437X(03)00048-0

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Muscular dystrophies are a genetically heterogeneous group of degenerative muscle disorders. Nearly 30 genes are known to give rise to various forms of muscular dystrophy, which differ in age of onset, severity, and muscle groups affected. The number of genes identified increases each year, adding to our understanding as well as revealing the overall complexity of the pathogenesis of these diseases.

引用

页码：231 / 238

页数：8

共 72 条

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