Ortho alkylation of aromatic ketimine with functionalized alkene by Rh(l) catalyst

被引：99

作者：

Lim, SG ^{[1
]}

Ahn, JA ^{[1
]}

Jun, CH ^{[1
]}

机构：

[1] Yonsei Univ, Dept Chem, CBMH, Seoul 120749, South Korea

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 25期

关键词：

D O I：

10.1021/ol048095n

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of the imine of aromatic ketones with functionalized alkenes was performed under a catalytic amount of (PPh3)(3)RhCl, and corresponding ortho-alkylated ketones were obtained after hydrolysis. A variety of functional groups in the alkene were tolerated in this ortho alkylation. This procedure expands the scope of ortho alkylation to the direct ortho functionalization of aromatic ketones.

引用

页码：4687 / 4690

页数：4

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