Semi-continuous nanofiltration-coupled Heck reactions as a new approach to improve productivity of homogeneous catalysts

被引：94

作者：

Nair, D

Scarpello, JT

White, LS

dos Santos, LMF

Vankelecom, IFJ

Livingston, AG ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Dept Chem Engn, London SW7 2BY, England

[2] WR Grace & Co Conn, Columbia, MD 21044 USA

[3] GlaxoSmithKline, Harlow CM19 5AW, Essex, England

[4] Katholieke Univ Leuven, Ctr Surface Chem & Catalysis, B-3001 Louvain, Belgium

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 46期

基金：

英国工程与自然科学研究理事会;

关键词：

Heck reaction; homogeneous catalysis; nanofiltration; catalyst recycle;

D O I：

10.1016/S0040-4039(01)01734-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Substantial increase in homogeneous catalyst productivity for a well known Heck coupling was achieved by nanofiltration-coupled catalysis. The use of nanofiltration membranes enabled catalyst separation and allowed subsequent catalyst recycle and reuse. This new technique demonstrated potential for general applicability to homogeneously catalysed organic syntheses. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

收藏

页码：8219 / 8222

页数：4

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