Current status and future outlook of nano-based systems for burn wound management

被引:38
作者
Abazari, Morteza [1 ]
Ghaffari, Azadeh [2 ,3 ]
Rashidzadeh, Hamid [4 ]
Badeleh, Safa Momeni [2 ]
Maleki, Yaser [5 ]
机构
[1] Zanjan Univ Med Sci, Sch Pharm, Dept Pharmaceut Nanotechnol, Zanjan, Iran
[2] Zanjan Univ Med Sci, Sch Pharm, Dept Food & Drug Control, Zanjan, Iran
[3] Zanjan Univ Med Sci, Pharmaceut Nanotechnol Res Ctr, Zanjan, Iran
[4] Zanjan Univ Med Sci, Sch Pharm, Dept Pharmaceut Biomat, Zanjan, Iran
[5] Inst Adv Studies Basic Sci, Dept Nanochem, Zanjan, Iran
关键词
burn wound; laboratory and animal models; multicomposites; nanomedicine; nanotechnology-based systems; nanoparticles; scaffolds; EPIDERMAL-GROWTH-FACTOR; DRUG-DELIVERY SYSTEMS; CHITOSAN ACETATE BANDAGE; SILVER SULFADIAZINE; IN-VITRO; ANIMAL-MODELS; ELECTROSPUN NANOFIBERS; CLINDAMYCIN PHOSPHATE; BACTERIAL CELLULOSE; SKIN REGENERATION;
D O I
10.1002/jbm.b.34535
中图分类号
R318 [生物医学工程];
学科分类号
100103 [病原生物学];
摘要
Wound healing process is a natural and intricate response of the body to its injuries and includes a well-orchestrated sequence of biochemical and cellular phenomena to restore the integrity of skin and injured tissues. Complex nature and associated complications of burn wounds lead to an incomplete and prolonged recovery of these types of wounds. Among different materials and systems which have been used in treating the wounds, nanotechnology driven therapeutic systems showed a great opportunity to improvement and enhancement of the healing process of different type of wounds. The aim of this study is to provide an overview of the recent studies about the various nanotechnology-based management of burn wounds and the future outlook of these systems in this area. Laboratory and animal models for assessing the efficacy of these systems in burn wound management also discussed.
引用
收藏
页码:1934 / 1952
页数:19
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