Phase-resolved optical frequency domain imaging

被引:266
作者
Vakoc, BJ
Yun, SH
de Boer, JF
Tearney, GJ
Bouma, BE
机构
[1] Harvard Univ, Sch Med, Boston, MA 02114 USA
[2] Massachusetts Gen Hosp, Wellman Ctr Photomed, Boston, MA 02114 USA
来源
OPTICS EXPRESS | 2005年 / 13卷 / 14期
关键词
D O I
10.1364/OPEX.13.005483
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Phase-resolved Doppler optical coherence tomography has been used to image blood flow dynamics in various tissues using both time-domain and spectral-domain optical coherence tomography techniques. In this manuscript, we present phase-resolved Doppler imaging with a highspeed optical frequency domain imaging system. We demonstrate that by correcting for spurious timing-induced phase errors, excellent flow sensitivity can be achieved, limited only by the imaging signal-to-noise ratio. Conventional and Doppler images showing flow in an Intralipid phantom and in human skin are presented. Additionally, we demonstrate the ability of phase-resolved OFDI to measure high flow rates without the deleterious effects of fringe washout. (C) 2005 Optical Society of America.
引用
收藏
页码:5483 / 5493
页数:11
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