Two New Triterpenoids from Lysimachia heterogenea Klatt and Evaluation of Their Cytotoxicity

被引:10
作者
Huang, Xin-An [1 ]
Shen, Xiao-Ling [1 ]
Hu, Ying-Jie [1 ]
Liu, Ya-Ming [2 ]
Liu, Kang-Lun [1 ]
Zhang, Feng-Xue [1 ]
Zhou, Xin-Xin [3 ]
机构
[1] Guangzhou Univ Chinese Med, Inst Trop Med, Guangzhou 510405, Guangdong, Peoples R China
[2] Guangzhou Univ Chinese Med, Affiliated Hosp 1, Guangzhou 510405, Guangdong, Peoples R China
[3] Guangzhou Univ Chinese Med, Coll Vocat & Tech Educ, Guangzhou 510405, Guangdong, Peoples R China
关键词
Lysimachia heterogenea Klatt; triterpenoids; cytotoxicity;
D O I
10.3390/molecules16098076
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
070307 [化学生物学]; 071010 [生物化学与分子生物学];
摘要
Two new 13,28-epoxy oleanane-type triterpenoids, namely heterogenoside E and F, were isolated from Lysimachia heterogenea Klatt, together with the eight known compounds: palmitic acid, beta-stigmasterol, kaempferol, quercetin, hyperin, isorhamnetin, isorhamnetin-3-O-galactopyranoside and anagallisin C. Heterogenoside F possesses acetoxyl groups at the unusual C-21 and C-22 positions of its oleanane skeleton. The cytotoxic activities of anagallisin C, heterogenoside E and F were weak.
引用
收藏
页码:8076 / 8082
页数:7
相关论文
共 11 条
[1]
Flavonol triglycosides from the leaves of Hammada scoparia (POMEL) Iljin [J].
Ben Salah, H ;
Jarraya, R ;
Martin, MT ;
Veitch, NC ;
Grayer, RJ ;
Simmonds, MSJ ;
Damak, M .
CHEMICAL & PHARMACEUTICAL BULLETIN, 2002, 50 (09) :1268-1270
[2]
Cytotoxic triterpenoid saponins of Albizia gummifera from the Madagascar rain forest [J].
Cao, Shugeng ;
Norris, Andrew ;
Miller, James S. ;
Ratovoson, Fidy ;
Razafitsalama, Jeremi ;
Andriantsiferana, Rabodo ;
Rasamison, Vincent E. ;
TenDyke, Karen ;
Suh, Ted ;
Kingston, David G. I. .
JOURNAL OF NATURAL PRODUCTS, 2007, 70 (03) :361-366
[3]
A new hydroquinone diglucoside from Lysimachia fordiana [J].
Huang, XA ;
Yang, RZ .
CHEMISTRY OF NATURAL COMPOUNDS, 2004, 40 (05) :457-459
[4]
A new poly-substituted benzaldehyde from the leaves of Lysimachia fordiana Oliv. [J].
Huang, Xin-an ;
Yang, Ren-zhou ;
Deng, Wen-di .
MOLECULES, 2007, 12 (01) :43-48
[5]
Four new cytotoxic oligosaccharidic derivatives of 12-oleanene from Lysimachia heterogenea Klatt [J].
Huang, Xin-an ;
Liang, Yong-ju ;
Cai, Xiao-ling ;
Feng, Xiao-quan ;
Zhang, Chuan-hai ;
Fu, Li-wu ;
Deng, Wen-di .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 19 (23) :6515-6518
[6]
Huang Xin-An, 2007, Zhongguo Zhong Yao Za Zhi, V32, P596
[7]
Huang XinAn Huang XinAn, 2007, Journal of Tropical and Subtropical Botany, V15, P175
[8]
Two new triterpenoid glycosides isolated from Aesculus assamica GRIFF [J].
Liu, HW ;
Zhang, X ;
Gao, H ;
Wang, NL ;
Jin, SL ;
Cai, B ;
Yao, XS ;
Cai, GP .
CHEMICAL & PHARMACEUTICAL BULLETIN, 2005, 53 (10) :1310-1313
[9]
STRUCTURE ELUCIDATION OF 4 NEW TRITERPENOID OLIGOGLYCOSIDES FROM ANAGALLIS-ARVENSIS [J].
MAHATO, SB ;
SAHU, NP ;
ROY, SK ;
SEN, S .
TETRAHEDRON, 1991, 47 (28) :5215-5230
[10]
Preparative Separation of Axifolin-3-Glucoside, Hyperoside and Amygdalin from Plant Extracts by High Speed Countercurrent Chromatography [J].
Wei, Yun ;
Xie, Qianqian ;
Ito, Yoichiro .
JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, 2009, 32 (07) :1010-1022