The RCSB Protein Data Bank: redesigned web site and web services

被引：501

作者：

Rose, Peter W. ^{[1
]}

Beran, Bojan ^{[1
]}

Bi, Chunxiao ^{[1
]}

Bluhm, Wolfgang F. ^{[1
]}

Dimitropoulos, Dimitris ^{[1
]}

Goodsell, David S. ^{[2
]}

Prlic, Andreas ^{[1
]}

Quesada, Martha ^{[3
]}

Quinn, Gregory B. ^{[1
]}

Westbrook, John D. ^{[3
]}

Young, Jasmine ^{[3
]}

Yukich, Benjamin ^{[1
]}

Zardecki, Christine ^{[3
]}

Berman, Helen M. ^{[3
]}

Bourne, Philip E. ^{[1
,4
]}

机构：

[1] Univ Calif San Diego, San Diego Supercomp Ctr, La Jolla, CA 92093 USA

[2] Scripps Res Inst, Dept Mol Biol, La Jolla, CA 92093 USA

[3] Rutgers State Univ, Dept Chem & Chem Biol, Piscataway, NJ 08854 USA

[4] Univ Calif San Diego, Skaggs Sch Pharm & Pharmaceut Sci, La Jolla, CA 92093 USA

来源：

NUCLEIC ACIDS RESEARCH | 2011年 / 39卷

基金：

美国国家科学基金会;

关键词：

CRYSTAL-STRUCTURE; STRUCTURE ALIGNMENT; FRAGMENT; SYSTEM;

D O I：

10.1093/nar/gkq1021

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The RCSB Protein Data Bank (RCSB PDB) web site (http://www.pdb.org) has been redesigned to increase usability and to cater to a larger and more diverse user base. This article describes key enhancements and new features that fall into the following categories: (i) query and analysis tools for chemical structure searching, query refinement, tabulation and export of query results; (ii) web site customization and new structure alerts; (iii) pair-wise and representative protein structure alignments; (iv) visualization of large assemblies; (v) integration of structural data with the open access literature and binding affinity data; and (vi) web services and web widgets to facilitate integration of PDB data and tools with other resources. These improvements enable a range of new possibilities to analyze and understand structure data. The next generation of the RCSB PDB web site, as described here, provides a rich resource for research and education.

引用

页码：D392 / D401

页数：10

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