Domino coupling relay approach to polycyclic pyrrole-2-carboxylates

被引：209

作者：

Yamamoto, Y ^{[1
]}

Hayashi, H ^{[1
]}

Saigoku, T ^{[1
]}

Nishiyama, H ^{[1
]}

机构：

[1] Nagoya Univ, Grad Sch Engn, Dept Appl Chem, Chikusa Ku, Nagoya, Aichi 4648603, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 127卷 / 31期

关键词：

D O I：

10.1021/ja053408a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

CuBr2-catalyzed three-component coupling of N-benzylallylamine, ethyl glyoxalate, and terminal alkynes afforded glycine-tethered 1,6-enynes, which were further transformed into polycyclic pyrrole-2-carboxylates via novel cycloisomerization/Diels-Alder cycloaddition/dehydrogenation sequence under iridium-catalyzed conditions. Copyright © 2005 American Chemical Society.

引用

页码：10804 / 10805

页数：2

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