Mechanisms of Ca2+-dependent transcription

被引：109

作者：

Mellström, B ^{[1
]}

Naranjo, JR ^{[1
]}

机构：

[1] CSIC, Dept Biol Mol & Celular, CNB, Ctr Nacl Biotecnol, E-28049 Madrid, Spain

来源：

CURRENT OPINION IN NEUROBIOLOGY | 2001年 / 11卷 / 03期

关键词：

D O I：

10.1016/S0959-4388(00)00213-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Ca2+ has a central role in coupling synaptic activity and transcriptional responses. Recent studies have focused on Ca2+-dependent nuclear mechanisms that bring to the nucleosomal level cascades of events initiated in the submembranous space at the synapse. In addition, a new Ca2+-dependent interaction between a calcium sensor and DNA has been shown to regulate transcription directly.

引用

页码：312 / 319

页数：8

共 71 条

[51] A role for nuclear inositol 1,4,5-trisphosphate kinase in transcriptional control [J].

Odom, AR ;

Stahlberg, A ;

Wente, SR ;

York, JD .

SCIENCE, 2000, 287 (5460) :2026-2029

[52] A novel type of calmodulin interaction in the inhibition of basic helix-loop-helix transcription factors [J].

Onions, J ;

Hermann, S ;

Grundström, T .

BIOCHEMISTRY, 2000, 39 (15) :4366-4374

[53] Cell signalling - Control of free calcium in plant cell nuclei [J].

Pauly, N ;

Knight, MR ;

Thuleau, P ;

van der Luit, AH ;

Moreau, M ;

Trewavas, AJ ;

Ranjeva, R ;

Mazars, C .

NATURE, 2000, 405 (6788) :754-755

[54] Transcription factors of the NFAT family: Regulation and function [J].

Rao, A ;

Luo, C ;

Hogan, PG .

ANNUAL REVIEW OF IMMUNOLOGY, 1997, 15 :707-747

[55] Cerebellar defects in Ca2+/calmodulin kinase IV-deficient mice [J].

Ribar, TJ ;

Rodriguiz, RM ;

Khiroug, L ;

Wetsel, WC ;

Augustine, GJ ;

Means, AR .

JOURNAL OF NEUROSCIENCE, 2000, 20 (22)

[56] Calcium signaling in the cell nucleus [J].

Santella, L ;

Carafoli, E .

FASEB JOURNAL, 1997, 11 (13) :1091-1109

[57]

SANZ C, 2001, IN PRESS EMBO J

[58] Requirement of Rsk-2 for epidermal growth factor-activated phosphorylation of histone H3 [J].

Sassone-Corsi, P ;

Mizzen, CA ;

Cheung, P ;

Crosio, C ;

Monaco, L ;

Jacquot, S ;

Hanauer, A ;

Allis, CD .

SCIENCE, 1999, 285 (5429) :886-891

[59] CREB: A stimulus-induced transcription factor activated by a diverse array of extracellular signals [J].

Shaywitz, AJ ;

Greenberg, ME .

ANNUAL REVIEW OF BIOCHEMISTRY, 1999, 68 :821-861

[60] CREB - A CA2+-REGULATED TRANSCRIPTION FACTOR PHOSPHORYLATED BY CALMODULIN-DEPENDENT KINASES [J].

SHENG, M ;

THOMPSON, MA ;

GREENBERG, ME .

SCIENCE, 1991, 252 (5011) :1427-1430

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