Mechanisms of Ca2+-dependent transcription

被引：109

作者：

Mellström, B ^{[1
]}

Naranjo, JR ^{[1
]}

机构：

[1] CSIC, Dept Biol Mol & Celular, CNB, Ctr Nacl Biotecnol, E-28049 Madrid, Spain

来源：

CURRENT OPINION IN NEUROBIOLOGY | 2001年 / 11卷 / 03期

关键词：

D O I：

10.1016/S0959-4388(00)00213-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Ca2+ has a central role in coupling synaptic activity and transcriptional responses. Recent studies have focused on Ca2+-dependent nuclear mechanisms that bring to the nucleosomal level cascades of events initiated in the submembranous space at the synapse. In addition, a new Ca2+-dependent interaction between a calcium sensor and DNA has been shown to regulate transcription directly.

引用

页码：312 / 319

页数：8