Graphene oxide-protected DNA probes for multiplex microRNA analysis in complex biological samples based on a cyclic enzymatic amplification method

被引：199

作者：

Cui, Liang ^{[1
]}

Lin, Xiaoyan ^{[1
]}

Lin, Ninghang ^{[1
]}

Song, Yanling ^{[1
]}

Zhu, Zhi ^{[1
]}

Chen, Xi ^{[1
]}

Yang, Chaoyong James ^{[1
]}

机构：

[1] Xiamen Univ, Key Lab Analyt Sci, Key Lab Chem Biol Fujian Prov, Key Lab Phys Chem Solid Surfaces,Coll Chem & Chem, Xiamen 361005, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 02期

关键词：

ROLLING-CIRCLE AMPLIFICATION;

D O I：

10.1039/c1cc15412e

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

Based on graphene oxide-protected DNA probes, we have developed a cyclic enzymatic amplification method for sensitive miRNA detection in complex biological samples. By using the quenching nature of graphene oxide for multiple fluorophores, this method can distinguish highly similar miRNA sequences and detect them simultaneously.

引用

收藏

页码：194 / 196

页数：3

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