Pyrido[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-diones:: Synthesis, cyclometalation, and protein kinase inhibition

被引：42

作者：

Bregman, H ^{[1
]}

Williams, DS ^{[1
]}

Meggers, E ^{[1
]}

机构：

[1] Univ Penn, Dept Chem, Philadelphia, PA 19104 USA

来源：

SYNTHESIS-STUTTGART | 2005年 / 09期

关键词：

pyridocarbazoles; photocyclization; cyclometalation; ruthenium; protein kinase inhibitors;

D O I：

10.1055/s-2005-865331

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthetic routes to pyrido[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-diones are disclosed and examples for their subsequent transformations into cyclometalated protein kinase inhibitors are presented.

引用

页码：1521 / 1527

页数：7

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