A novel method for synthesis of arylacetic acids from aldehydes, N-(2,3,4,6-tetra-O-pivaloylated-D-glucopyranosyl)amine and trimethylsilylcyanide

被引：28

作者：

Zhou, GB

Zhang, PF ^{[1
]}

Pan, YJ

机构：

[1] Hangzhou Teachers Coll, Dept Chem, Hangzhou 310012, Peoples R China

[2] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China

来源：

TETRAHEDRON | 2005年 / 61卷 / 23期

基金：

中国国家自然科学基金;

关键词：

arylacetic acids; N-(2.3.4,6-tetra-O-pivaloylated-D-glucopryanosyl)amine; aldehyde; triethylsilylcyanide;

D O I：

10.1016/j.tet.2005.03.095

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel synthetic approach for the preparation of arylacetic acids via the reaction of aldehydes, N-(2,3,4,6-tetra-O-pivaloylated-D-glucopyranosyl)amine and trimethylsilylcyanide was developed, in which the N-(2,3,4,6-tetra-O-pivaloylated-D-glucopyranosyl)amine can be recycled conveniently, and reused efficiently. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：5671 / 5677

页数：7

共 46 条

[1] Additions of organometallic reagents to C=N bonds: Reactivity and selectivity [J].