Biology of chromatin dynamics

被引:52
作者
Hsieh, TF [1 ]
Fischer, RL [1 ]
机构
[1] Univ Calif Berkeley, Dept Plant & Microbial Biol, Berkeley, CA 94720 USA
关键词
chromatin remodeling; epigenetic inheritance; histone modification; DNA methylation; RNA interference;
D O I
10.1146/annurev.arplant.56.032604.144118
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
During the development of a multicellular organism, cell differentiation involves activation and repression of transcription programs that must be stably maintained during subsequent cell divisions. Chromatin remodeling plays a crucial role in regulating chromatin states that conserve transcription programs and provide a mechanism for chromatin states to be maintained as cells proliferate, a process referred to as epigenetic inheritance. A large number of factors and protein complexes are now known to be involved in regulating the dynamic states of chromatin structure. Their biological functions and molecular mechanisms are beginning to be revealed.
引用
收藏
页码:327 / 351
页数:25
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