Assembling amperometric biosensors for clinical diagnostics

被引：96

作者：

Soledad Belluzo, Maria ^{[1
]}

Elida Ribone, Maria ^{[1
]}

Marina Lagier, Claudia ^{[1
]}

机构：

[1] Univ Nacl Rosario, Fac Ciencias Bioquim & Farmaceut, Dept Analyt Chem, RA-2000 Rosario, Santa Fe, Argentina

来源：

SENSORS | 2008年 / 8卷 / 03期

关键词：

biosensor; electrochemical; amperometric; clinical diagnosis;

D O I：

10.3390/s8031366

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Clinical diagnosis and disease prevention routinely require the assessment of species determined by chemical analysis. Biosensor technology offers several benefits over conventional diagnostic analysis. They include simplicity of use, specificity for the target analyte, speed to arise to a result, capability for continuous monitoring and multiplexing, together with the potentiality of coupling to low-cost, portable instrumentation. This work focuses on the basic lines of decisions when designing electron-transfer-based biosensors for clinical analysis, with emphasis on the strategies currently used to improve the device performance, the present status of amperometric electrodes for biomedicine, and the trends and challenges envisaged for the near future.

引用

页码：1366 / 1399

页数：34

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