A graphene oxide-peptide fluorescence sensor tailor-made for simple and sensitive detection of matrix metalloproteinase 2

被引：102

作者：

Feng, Duan ^{[1
]}

Zhang, Yangyang ^{[1
]}

Feng, Tingting ^{[1
]}

Shi, Wen ^{[1
]}

Li, Xiaohua ^{[1
]}

Ma, Huimin ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Chem, Key Lab Analyt Chem Living Biosyst, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 38期

关键词：

PLATFORM; PROBE; NANOTUBES; DELIVERY; ASSAY;

D O I：

10.1039/c1cc13975d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A graphene oxide-peptide based fluorescence sensor has been developed for matrix metalloproteinase 2 (MMP2), and its applicability has been demonstrated by monitoring the concentration of MMP2 secreted by HeLa cells, revealing that HeLa cells with a density of 5.48 x 10(5) cells per mL can produce 22 nM in cell culture media in 24 h.

引用

页码：10680 / 10682

页数：3

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