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The synthesis of Ambrox®-like compounds starting from (+)-larixol.: Part 2

被引：22
作者：
Bolster, MG
Lagnel, BMF
Jansen, BJM
Morin, C
de Groot, A
机构：
[1] Univ Wageningen & Res Ctr, Organ Chem Lab, NL-6703 HB Wageningen, Netherlands
[2] Univ Grenoble 1, CNRS, UMR 5616, Etud Dynam & Struct Select Lab, F-38041 Grenoble, France
来源：
TETRAHEDRON | 2001年 / 57卷 / 39期
关键词：
larixol; Ambrox (R)-like compounds; Delta(6)-Ambroxene;
D O I：
10.1016/S0040-4020(01)00818-3
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Several Ambroxe((R))-like compounds were synthesized in an enantiomerically pure form, and in relatively short procedures, starting from (+)-larixol. Triol 5 and enone 6 are important intermediates in these syntheses. The formation of Delta (6)-Ambrox((R))-type ethers was achieved by a new cyclization approach via ionization of the C(6)-allylic alcohol in ring B. (C) 2001 Elsevier Science Ltd. All rights reserved.
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收藏
页码：8369 / 8379
页数：13
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