Isolation and characterization of di- and tri-mannosyl-cyclomaltoheptaoses (β-cyclodextrins) produced by reverse action of α-mannosidase from jack bean

被引：11

作者：

Koizumi, K

Tanimoto, T

Okada, Y

Takeyama, S

Hamayasu, K

Hashimoto, H

Kitahata, S

机构：

[1] Mukogawa Womens Univ, Sch Pharmaceut Sci, Nishinomiya, Hyogo 6638179, Japan

[2] Bio Res Corp Yokohama, Tsurumi Ku, Yokohama, Kanagawa 2300053, Japan

[3] Osaka Municipal Tech Res Inst, Jyoto Ku, Osaka 5360025, Japan

来源：

CARBOHYDRATE RESEARCH | 1998年 / 314卷 / 1-2期

关键词：

di-mannosyl-cyclomaltoheptaose; tri-mannosyl-cyclomaltoheptaose; jack bran alpha-mannosidase; HPLC; FABMS; NMR; enzymatic method;

D O I：

10.1016/S0008-6215(98)00267-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Di- and tri-mannosyl-cyclomaltoheptaoses (beta-cyclodextrins, beta CDs), which were synthesized together with mono-mannosyl-beta CD in a large-scale production by reverse action of alpha-mannosidase from jack bean, were isolated and purified by HPLC. The structures of seven isomers of di-mannosyl-beta CD and six isomers of tri-mannosyl-beta CD were elucidated by FABMS and NMR spectroscopy, and by enzymatic methods. (C) 1998 Elsevier Science Ltd. All rights reserved.

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页码：115 / 125

页数：11

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