Non-coding RnA transcription: turning on neighbours

被引:28
作者
Carninci, Piero [1 ]
机构
[1] RIKEN, Omics Sci Ctr, Yokohama, Kanagawa, Japan
关键词
D O I
10.1038/ncb0908-1023
中图分类号
Q2 [细胞生物学];
学科分类号
071009 [细胞生物学]; 090102 [作物遗传育种];
摘要
Even though less than 2% of the mammalian genome encodes proteins, a significant fraction can be transcribed into non-coding RNAs. An elegant study identifies a function for non-coding RNA transcription in activating neighbouring genes.
引用
收藏
页码:1023 / 1024
页数:3
相关论文
共 11 条
[1]
Global identification of human transcribed sequences with genome tiling arrays [J].
Bertone, P ;
Stolc, V ;
Royce, TE ;
Rozowsky, JS ;
Urban, AE ;
Zhu, XW ;
Rinn, JL ;
Tongprasit, W ;
Samanta, M ;
Weissman, S ;
Gerstein, M ;
Snyder, M .
SCIENCE, 2004, 306 (5705) :2242-2246
[2]
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project [J].
Birney, Ewan ;
Stamatoyannopoulos, John A. ;
Dutta, Anindya ;
Guigo, Roderic ;
Gingeras, Thomas R. ;
Margulies, Elliott H. ;
Weng, Zhiping ;
Snyder, Michael ;
Dermitzakis, Emmanouil T. ;
Stamatoyannopoulos, John A. ;
Thurman, Robert E. ;
Kuehn, Michael S. ;
Taylor, Christopher M. ;
Neph, Shane ;
Koch, Christoph M. ;
Asthana, Saurabh ;
Malhotra, Ankit ;
Adzhubei, Ivan ;
Greenbaum, Jason A. ;
Andrews, Robert M. ;
Flicek, Paul ;
Boyle, Patrick J. ;
Cao, Hua ;
Carter, Nigel P. ;
Clelland, Gayle K. ;
Davis, Sean ;
Day, Nathan ;
Dhami, Pawandeep ;
Dillon, Shane C. ;
Dorschner, Michael O. ;
Fiegler, Heike ;
Giresi, Paul G. ;
Goldy, Jeff ;
Hawrylycz, Michael ;
Haydock, Andrew ;
Humbert, Richard ;
James, Keith D. ;
Johnson, Brett E. ;
Johnson, Ericka M. ;
Frum, Tristan T. ;
Rosenzweig, Elizabeth R. ;
Karnani, Neerja ;
Lee, Kirsten ;
Lefebvre, Gregory C. ;
Navas, Patrick A. ;
Neri, Fidencio ;
Parker, Stephen C. J. ;
Sabo, Peter J. ;
Sandstrom, Richard ;
Shafer, Anthony .
NATURE, 2007, 447 (7146) :799-816
[3]
The transcriptional landscape of the mammalian genome [J].
Carninci, P ;
Kasukawa, T ;
Katayama, S ;
Gough, J ;
Frith, MC ;
Maeda, N ;
Oyama, R ;
Ravasi, T ;
Lenhard, B ;
Wells, C ;
Kodzius, R ;
Shimokawa, K ;
Bajic, VB ;
Brenner, SE ;
Batalov, S ;
Forrest, ARR ;
Zavolan, M ;
Davis, MJ ;
Wilming, LG ;
Aidinis, V ;
Allen, JE ;
Ambesi-Impiombato, X ;
Apweiler, R ;
Aturaliya, RN ;
Bailey, TL ;
Bansal, M ;
Baxter, L ;
Beisel, KW ;
Bersano, T ;
Bono, H ;
Chalk, AM ;
Chiu, KP ;
Choudhary, V ;
Christoffels, A ;
Clutterbuck, DR ;
Crowe, ML ;
Dalla, E ;
Dalrymple, BP ;
de Bono, B ;
Della Gatta, G ;
di Bernardo, D ;
Down, T ;
Engstrom, P ;
Fagiolini, M ;
Faulkner, G ;
Fletcher, CF ;
Fukushima, T ;
Furuno, M ;
Futaki, S ;
Gariboldi, M .
SCIENCE, 2005, 309 (5740) :1559-1563
[4]
Multifaceted mammalian transcriptome [J].
Carninci, Piero ;
Yasuda, Jun ;
Hayashizaki, Yoshihide .
CURRENT OPINION IN CELL BIOLOGY, 2008, 20 (03) :274-280
[5]
Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution [J].
Cheng, J ;
Kapranov, P ;
Drenkow, J ;
Dike, S ;
Brubaker, S ;
Patel, S ;
Long, J ;
Stern, D ;
Tammana, H ;
Helt, G ;
Sementchenko, V ;
Piccolboni, A ;
Bekiranov, S ;
Bailey, DK ;
Ganesh, M ;
Ghosh, S ;
Bell, I ;
Gerhard, DS ;
Gingeras, TR .
SCIENCE, 2005, 308 (5725) :1149-1154
[6]
Human cis natural antisense transcripts initiated by transposable elements [J].
Conley, Andrew B. ;
Miller, Wolfgang J. ;
Jordan, I. King .
TRENDS IN GENETICS, 2008, 24 (02) :53-56
[7]
Ripples from neighbouring transcription [J].
Ebisuya, Miki ;
Yamamoto, Takuya ;
Nakajima, May ;
Nishida, Eisuke .
NATURE CELL BIOLOGY, 2008, 10 (09) :1106-1113
[8]
RNA maps reveal new RNA classes and a possible function for pervasive transcription [J].
Kapranov, Philipp ;
Cheng, Jill ;
Dike, Sujit ;
Nix, David A. ;
Duttagupta, Radharani ;
Willingham, Aarron T. ;
Stadler, Peter F. ;
Hertel, Jana ;
Hackermueller, Joerg ;
Hofacker, Ivo L. ;
Bell, Ian ;
Cheung, Evelyn ;
Drenkow, Jorg ;
Dumais, Erica ;
Patel, Sandeep ;
Helt, Gregg ;
Ganesh, Madhavan ;
Ghosh, Srinka ;
Piccolboni, Antonio ;
Sementchenko, Victor ;
Tammana, Hari ;
Gingeras, Thomas R. .
SCIENCE, 2007, 316 (5830) :1484-1488
[9]
Antisense transcription in the mammalian transcriptome [J].
Katayama, S ;
Tomaru, Y ;
Kasukawa, T ;
Waki, K ;
Nakanishi, M ;
Nakamura, M ;
Nishida, H ;
Yap, CC ;
Suzuki, M ;
Kawai, J ;
Suzuki, H ;
Carninci, P ;
Hayashizaki, Y ;
Wells, C ;
Frith, M ;
Ravasi, T ;
Pang, KC ;
Hallinan, J ;
Mattick, J ;
Hume, DA ;
Lipovich, L ;
Batalov, S ;
Engström, PG ;
Mizuno, Y ;
Faghihi, MA ;
Sandelin, A ;
Chalk, AM ;
Mottagui-Tabar, S ;
Liang, Z ;
Lenhard, B ;
Wahlestedt, C .
SCIENCE, 2005, 309 (5740) :1564-1566
[10]
RNA regulation: a new genetics? [J].
Mattick, JS .
NATURE REVIEWS GENETICS, 2004, 5 (04) :316-323